Van de Ven Brace Ends The Toffees' Unbeaten Streak at New Stadium
The Dutch defender emerged as the first backline player to score twice in a English top-flight game for Spurs since Jan Vertonghen in March 2013.
At a glance
The Spurs defender nods home two times in first half
Everton's defender has goal disallowed after video check
Senegalese midfielder nets third in dying moments
This loss is the Merseyside club's first at Hill Dickinson Stadium
Micky van de Ven scored on two occasions as Tottenham extended their winning streak on the road in the Premier League and delivered Everton their initial loss at their new home.
The Toffees were unbeaten in their last five matches at their new ground at Bramley-Moore Dock, having left Goodison Park behind after 133 years at the end of the previous campaign.
But Tottenham's leader Van de Ven struck on two occasions from set-pieces in the opening 45 minutes to put their impressive record at risk, and they were failed to turn it around before the midfielder - set up by ex-Everton forward Richarlison - nodded in a final goal to seal the victory.
Jake O'Brien believed he had equalized the scores five minutes after the defender's opener, glancing a bullet header past the Spurs keeper from an set-piece.
Beto, meanwhile, failed to convert a handful of opportunities, while the Italian goalkeeper made a succession of excellent stops to guarantee Tottenham went five matches on the road unbeaten in the Premier League.
But the video assistant referee intervened, instructing Craig Pawson to review the goal on the screen and the official decided that Jack Grealish and the attacker were in an illegal position and had impeded with the Tottenham goalkeeper.
This victory moves the manager's team into third place in the Premier League, a handful of points off local foes and table-toppers Arsenal.
The Merseyside club remain in 14th position and sit six points ahead of the drop zone.
Tottenham analysis: Van de Ven excels in role at each end of the field
Following a uninspiring midweek performance in the Champions League against Monaco, where they managed a only attempts on target, Frank chose the French striker in attack instead of former Toffees player the Brazilian.
The summer signing was failed to make much of an impact before being replaced for the substitute after an hour on the pitch, but it turns out he wasn't needed in the end.
Centre-back Van de Ven transformed into an offensive threat to be feared.
Tottenham's first goal came from a well-worked corner routine, with Rodrigo Bentancur directing the ball back across the face of goal for an unmarked the defender to head home.
And the captain - filling in as skipper in the Argentine's unavailability - added his next goal in first-half stoppage time as he outjumped the England keeper to nod in.
The Dutchman was equally outstanding in defensive duties, partnering well with his defensive colleague as the pair dealt superbly with the numerous deliveries thrown their way by the opposition.
Toffees breakdown: Toffees missing striker's instinct
Everton's new home had been a happy hunting ground, but it seems the freshness may have worn off slightly and supporters headed to the gates after the midfielder's third for Tottenham.
The break in the team's winning streak at home will not be a major concern for the manager, but their striker situation are.
The forward and the other striker - the Toffees' pair of established centre-forwards - had scored just one league goal between them before Sunday's match.
And they were failed to contribute to that poor record on a damp and dreary evening on in Liverpool.
Beto's form was epitomized when he chose to overhead kick a clear chance from close range, even with having room and time to reposition for a more conventional shot that would have challenged the keeper.
Barry, as well, was unable to make an impact after coming on for the starter in the second half.
It wasn't for a lack of opportunity. Most of the home side's offensive moves came through Grealish and the forward, who relentlessly delivered dangerous crosses into the Tottenham penalty area.
What next for these two sides?
Everton: The team head to Sunderland in the top flight on early November at 8 PM.
Spurs: Spurs go to St James' Park on Wednesday, 29 October for their fourth-round League Cup match against Newcastle.